In March 2020, SARS-CoV-2 based infections were declared ‘COVID-19 pandemic’ by the World Health Organization (WHO). Pandemic raised the necessity to design and develop genuine and sensitive tests for precise specific SARS-CoV-2 infections detection. Nanotechnological methods offer new ways to fight COVID-19. Nanomaterials are ideal for unique sensor platforms due to their easy manufacturing, chemically versatile properties. These materials are the most current components in SARS-CoV-2 testing since they have distinct properties, such as their large surface-to-volume ratios. Extensive surface interactions of the nanomaterials and the sensor and the analyte, these materials allow rapid and reliable detections with high sensitivity. Nanobiosensors are a valuable alternative to conventional laboratory devices for clinical and environmental analysis. They can combine the unique electrical and optical properties of nanomaterials with biological or synthetic molecules that are used as receptors for the selective detection of all types of analytes. In this webinar, various nanomaterial-based particular biosensor arrays are given in selected platforms.